Pulmonary Involvement in Systemic Onset Juvenile Arthritis: Current Status of the Problem

Autor:	Maria I. Kaleda, Irina P. Nikishina, Svetlana R. Rodionovskaya, Ekaterina V. Nikolaeva
Jazyk:	English<br />Russian
Rok vydání:	2021
Předmět:	systemic onset juvenile arthritis macrophage activation syndrome pulmonary involvement in children interstitial lung disease pulmonary alveolar proteinosis pulmonary hypertension Pediatrics RJ1-570
Zdroj:	Вопросы современной педиатрии, Vol 20, Iss 1, Pp 31-37 (2021)
Druh dokumentu:	article
ISSN:	1682-5527 1682-5535
DOI:	10.15690/vsp.v20i1.2234
Popis:	Systemic onset juvenile arthritis is the complex autoinflammatory disease with multigenic type of inheritance. It is characterized by significant systemic manifestations and unfavourable adverse events, among which macrophage activation syndrome and pulmonary involvement are playing crucial role. This article presents data on the frequency and features of the disease course, possible development predictors and clinical-radiological picture of pulmonary involvement in systemic onset juvenile arthritis. Possible factors (including hereditary) affecting the process of pulmonary involvement development and the role of genetically engineered biologic therapy are considered.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5efe80a6234d4675ad349ddcabbf9ee5 View record in DOAJ