Morphological Characteristics of Ruptured Brain Aneurysms: A Systematic Literature Review and Meta‐Analysis

Autor: Sebastian Sanchez, Meredith Hickerson, Rishi R. Patel, Dana Ghazaleh, Ranita Tarchand, Geeta S. Paranjape, Holly Pope, Santiago Ortega‐Gutierrez, John M. Pederson, David Hasan, Madhavan L. Raghavan, Edgar A. Samaniego
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Stroke: Vascular and Interventional Neurology, Vol 3, Iss 2 (2023)
Druh dokumentu: article
ISSN: 2694-5746
DOI: 10.1161/SVIN.122.000707
Popis: Background It is unclear what morphological features of brain aneurysms are better at predicting risk of rupture. We conducted a meta‐analysis to analyze the best morphological determinants of rupture status. Methods The Nested Knowledge platform was used to perform a search of articles reporting on aneurysm size, aspect ratio (AR), size ratio (SR), ellipticity index, nonsphericity index, and undulation index. The mean differences between ruptured and unruptured aneurysms were used to calculate effect sizes. Results A total of 63 studies with 13 025 aneurysms were included: 6966 ruptured aneurysms and 6059 unruptured aneurysms. Ruptured aneurysms had a larger size (P
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