Growth-coupled selection of synthetic modules to accelerate cell factory development

Autor: Enrico Orsi, Nico J. Claassens, Pablo I. Nikel, Steffen N. Lindner
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-5 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-25665-6
Popis: Synthetic biology has brought about a conceptual shift in our ability to redesign microbial metabolic networks. Combining metabolic pathway-modularization with growth-coupled selection schemes is a powerful tool that enables deep rewiring of the cell factories’ biochemistry for rational bioproduction.
Databáze: Directory of Open Access Journals