| Autor: |
Yuwen Sun, Zhaoshan Wang, Shufang Wu, Yuchen Zhang, Feng Shi |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Green Synthesis and Catalysis, Vol 3, Iss 1, Pp 84-88 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-5549 |
| DOI: |
10.1016/j.gresc.2021.11.003 |
| Popis: |
A Lewis acid-catalyzed [4 + 2] cycloaddition of 3-alkyl-2-vinylindoles with β,γ-unsaturated α-ketoesters has been established in the presence of Sc(OTf)3, which afforded a series of indole-containing pyran derivatives in generally good yields (up to 90% yield) with excellent diastereoselectivities (up to > 95:5 dr) under mild conditions. This approach not only enriches the chemistry of 3-alkyl-2-vinylindoles, but also has provided an atom-economic method for the synthesis of indole-containing pyran derivatives with potential bioactivity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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