Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up

Autor: Wen Liu, Xiaohong Zhang, Tie Zhao, Chenglong Zhou, Junxia Duan, Feijun Zhao
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Data in Brief, Vol 21, Iss , Pp 2237-2241 (2018)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2018.10.075
Popis: The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1,2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to determine whether T. pallidum DNA could be detected in different groups. Sixty paired serum samples from patients at follow-up were tested by RPR and recombinant Tp0971-, Tp0768-, Tp0462- and Tp92-based ELISA. Keywords: Treponema pallidum, Rabbit, RPR, ELISA
Databáze: Directory of Open Access Journals