Prognostic Factors after Surgical Treatment for Spinal Metastases

Autor: Kazuhiro Murotani, Shunsuke Fujibayashi, Bungo Otsuki, Takayoshi Shimizu, Takashi Sono, Eijiro Onishi, Hiroaki Kimura, Yasuyuki Tamaki, Naoya Tsubouchi, Masato Ota, Ryosuke Tsutsumi, Tatsuya Ishibe, Shuichi Matsuda
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Asian Spine Journal, Vol 18, Iss 3, Pp 390-397 (2024)
Druh dokumentu: article
ISSN: 1976-1902
1976-7846
DOI: 10.31616/asj.2023.0376
Popis: Study Design A retrospective multicenter case series was conducted. Purpose This study aimed to investigate survival and prognostic factors after surgery for a metastatic spinal tumor. Overview of Literature Prognostic factors after spinal metastasis surgery remain controversial. Methods A retrospective multicenter study was conducted. The study participants included 345 patients who underwent surgery for spinal metastases from 2010 to 2020 at nine referral spine centers in Japan. Data for each patient were extracted from medical records. To identify the factors predicting survival prognosis after surgery, univariate analyses were performed using a Cox proportional hazards model. Results The mean age was 65.9 years. Common primary tumors were lung (n=72), prostate (n=61), and breast (n=39), and 67.8% (n=234) presented with osteolytic lesions. The epidural spinal cord compression scale score 2 or 3 was recognized in 79.0% (n=271). Frankel grade A paralysis accounted for 1.4% (n=5), and 73.3% (n=253) were categorized as intermediate or high risk according to the new Katagiri score. The overall survival rates were -71.0% at 6 months, 57.4% at 12, and 43.3% at 24. In the univariate analysis, Frankel grade A (hazard ratio [HR], 3.59; 95% confidence interval [CI], 1.23–10.50; p
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