A temporary indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells

Autor: Tae Hyun Kim, Yang Wang, C. Ryan Oliver, Douglas H. Thamm, Laura Cooling, Costanza Paoletti, Kaylee J. Smith, Sunitha Nagrath, Daniel F. Hayes
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-09439-9
Popis: Ex vivo methods of circulating tumor cell (CTC) isolation use small blood volumes, limiting sensitivity and introducing analytical inaccuracies. The authors describe a proof-of-concept study of an in vivo aphaeresis system that continuously collects CTCs from a peripheral vein over several hours.
Databáze: Directory of Open Access Journals