Assessing XEN microstent’s one-year efficacy: independent of site variability

Autor: Caroline Bormann, Catharina Busch, Matus Rehak, Christian Thomas Scharenberg, Focke Ziemssen, Jan Darius Unterlauft
Jazyk: angličtina
Rok vydání: 2025
Předmět:
Zdroj: International Journal of Ophthalmology, Vol 18, Iss 1, Pp 86-93 (2025)
Druh dokumentu: article
ISSN: 2222-3959
2227-4898
DOI: 10.18240/ijo.2025.01.10
Popis: AIM: To evaluate the short-term efficacy of XEN45 Gel Stent (XEN) implantation for primary open angle glaucoma (POAG) and pseudoexfoliation (PEX) glaucoma across two university eye clinics, aiming to assess the impact of varying center-specific protocols during the first postoperative year. METHODS: We retrospectively examined 282 patients (183 in center 1, 99 in center 2), who underwent XEN microstent implantation for uncontrolled POAG or PEX glaucoma. Parameters including intraocular pressure (IOP), IOP-lowering medication count, best corrected visual acuity (BCVA), and postoperative complications were evaluated over 12mo. RESULTS: Post-implantation, center 1 reported a mean IOP reduction from 25.3±7.4 to 14.1±4.7 mm Hg (P
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