Intrathecal tigecycline is a safe and effective treatment for central nervous system infections

Autor:	Antonio Mastroianni, Valeria Vangeli, Maria Vittoria Mauro, Filippo Urso, Roberto Manfredi, Sonia Greco
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	tigecycline central nervous system bacterial infections intrathecal injections multi drug resistance Infectious and parasitic diseases RC109-216 Neurology. Diseases of the nervous system RC346-429
Zdroj:	Encephalitis, Vol 3, Iss 3, Pp 87-93 (2023)
Druh dokumentu:	article
ISSN:	2765-4559 2734-1461
DOI:	10.47936/encephalitis.2023.00010
Popis:	Both the safety and effectiveness of intrathecal tigecycline (TGC) for treatment of infections of the central nervous system (CNS) are discussed using the clinical findings from a study of a recent patient who came to our attention, along with a literature review. Although penetration into the CNS is low (approximately 11%), intraventricular TGC could help treat patients with severe post-neurosurgical CNS infections. The use of multiple routes of TGC administration appears to be encouraging and should be considered in managing life-threatening intraventricular infections.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/c5e3e78bfde543518a333a79ca46852f Zobrazit plný text záznamu View record in DOAJ