The epidemiology of obesity and the development of disorders of glucose metabolism according to a prospective study in Siberia

Autor: Vladimirovna Svetlana Mustafina, Sof'ya Konstantinovna Malyutina, Oksana Dmitrievna Rymar, Liliya Valer'evna Shcherbakova, Mikhail Ivanovich Voevoda
Jazyk: English<br />Russian
Rok vydání: 2015
Předmět:
Zdroj: Ожирение и метаболизм, Vol 12, Iss 4, Pp 14-28 (2015)
Druh dokumentu: article
ISSN: 2071-8713
2306-5524
DOI: 10.14341/omet2015414-28
Popis: Introduction: Persons who are overweight and obese have a higher risk of development of diabetes mellitus. In Russia, the epidemiological trends of glucose metabolism disorders in obese persons are understudied.Aim. To study the prevalence of overweight and obesity in a population sample aged 45–69 (Novosibirsk), and to assess the relationship between body mass index and 3-year dynamics of glucose metabolism disorders in a prospective cohort study.Material and Methods: A representative population sample of men and women 45–69 years old was examined in Novosibirsk in 2003–2005 (baseline survey, HAPIEE Project). In a prospective study 2,787 individuals without baseline diabetes who participated in the first and repeated surveys (2006–2008) were analyzed. The average duration of prospective follow–up comprised 3±0.01 years. Anthropometric measurements, biochemical assessment including lipids and carbohydrate metabolism were performed. Diabetes mellitus was defined by epidemiological criteria in patients with established diabetes history and in individuals with fasting blood glucose level ≥7,0mmol/l (WHO, 1999). The classification of obesity by BMI value was used according to WHO (1997).Results: In a population sample aged 45–69 in 2002–2006 the proportions of persons with BMI value ≥25 and
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