Popis: |
Objective:With regard to the correlation between T helper1/T helper2 (Th1/Th2) cell balance and 1α,25-dihydroxyvitamin D3, active metabolite of vitamin D, we studied Th1/Th2 cell balance by measuring levels of the cytokines interleukin (IL)-4, IL-10 and interferon- gamma (IFN-γ), which are important for immune response of patients with allergic rhinitis.Methods:Thirty adult patients diagnosed with allergic rhinitis (study group) and 40 healthy volunteers (control group) are examined in the research. IFN-γ, IL-4, IL-10, and total immunoglobulin E (IgE) levels from serum samples and vitamin D3 levels from plasma were determined in all patients.Results:In IgE, IL-4, IL-10, IFN-γ, and 1α,25-dihydroxyvitamin D3 levels (p |