Development of a Multiplex Tandem PCR (MT-PCR) Assay for the Detection of Emerging SARS-CoV-2 Variants

Autor: Richard Hale, Peter Crowley, Samir Dervisevic, Lindsay Coupland, Penelope R. Cliff, Saidat Ebie, Luke B. Snell, Joel Paul, Cheryl Williams, Paul Randell, Marcus Pond, Keith Stanley
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Viruses, Vol 13, Iss 10, p 2028 (2021)
Druh dokumentu: article
ISSN: 13102028
1999-4915
DOI: 10.3390/v13102028
Popis: The emergence of variants of SARS-CoV-2 has created challenges for the testing infrastructure. Although large-scale genome sequencing of SARS-CoV-2 has facilitated hospital and public health responses, access to sequencing facilities globally is variable and turnaround times can be significant, so there is a requirement for rapid and cost-effective alternatives. Applying a polymerase chain reaction (PCR)-based single nucleotide polymorphism (SNP) approach enables rapid (
Databáze: Directory of Open Access Journals