Pitfalls in estimation of glycosylated hemoglobin: A rare hemoglobin variant—Hb Hope

Autor: Anu Mathew, Ashok Rajagopal, Jasjeet Singh Wasir
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Diabetology, Vol 12, Iss 3, Pp 368-370 (2021)
Druh dokumentu: article
ISSN: 2078-7685
DOI: 10.4103/JOD.JOD_2_21
Popis: Hemoglobin (Hb) Hope is a rare Hb variant which is clinically silent but causes spuriously high glycated hemoglobin (HbA1c). We report a case of a 45-year-old gentleman, planned for elective total hip replacement, who presented with very high HbA1c with normal blood glucose and fructosamine levels. With the suspicion of erroneous HbA1c, an Hb electrophoresis was done, and he was found to have a rare hemoglobin variant called Hb Hope. We also reviewed almost all case reports of Hb Hope variant causing spuriously high HbA1c levels from India.
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