Choroidal and retinal thickness in patients with vitamin C deficiency using swept-source optical coherence tomography

Autor: Yiwen Qian, Luoziyi Wang, Xinfang Qiang, Huan Weng, Jing Jiang, Xin Che, Qingjian Li, Zhiliang Wang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Ophthalmology, Vol 22, Iss 1, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 1471-2415
DOI: 10.1186/s12886-022-02530-8
Popis: Abstract Background To investigate the effects of vitamin C on central retinal thickness and choroidal thickness. Methods A total of 69 patients diagnosed with vitamin C deficiency and 1:1 age- and gender-matched 69 healthy individuals with normal serum vitamin C were included in this study. Demographic characteristics of the individuals were collected. All patients underwent a comprehensive ophthalmic examination. Subfoveal choroidal thickness and retinal thickness were measured using a swept-source optical coherence tomography (SS-OCT). Results The average retinal thickness was 269.07 ± 13.51 μm in the vitamin C deficiency group and 276.92 ± 13.51 μm in the control group. The average choroidal thickness was 195.62 ± 66.40 μm in the in the vitamin C deficiency group and 238.86 ± 55.08 μm in the control group. There was a significant decrease in both average choroidal thickness and retinal thickness in vitamin C deficiency group compared with normal individuals (p
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