| Autor: |
Daisuke Nagasato, MD, PhD, Yuki Muraoka, MD, PhD, Mao Tanabe, MD, Naomi Nishigori, MD, Rie Osaka, MD, Yoshinori Mitamura, MD, PhD, Hitoshi Tabuchi, MD, PhD, Tomoaki Murakami, MD, PhD, Sotaro Ooto, MD, Kiyoshi Suzuma, MD, PhD, Akitaka Tsujikawa, MD, PhD |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Ophthalmology Science, Vol 4, Iss 2, Pp 100418- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2666-9145 |
| DOI: |
10.1016/j.xops.2023.100418 |
| Popis: |
Purpose: The aim of this study was to examine the effects of foveal thickness (FT) fluctuation (FTF) on 2-year visual and morphological outcomes of eyes with central retinal vein occlusion (CRVO) undergoing anti-VEGF treatment for recurrent macular edema (ME) based on a pro re nata regimen. Design: Retrospective, observational case series. Participants: We analyzed 141 treatment-naive patients (141 eyes) with CRVO-ME at a multicenter retinal practice. Methods: We assessed FT using OCT at each study visit. Patients were divided into groups 0, 1, 2, and 3 according to increasing FTF. Main Outcome Measures: We evaluated the logarithm of the minimal angle of resolution (logMAR) best-corrected visual acuity (BCVA), the length of the foveal ellipsoid zone (EZ) band defect measured using OCT, and the association of FTF with VA and EZ band defect length. Results: The mean baseline logMAR BCVA and FT were 0.65 ± 0.52 (Snellen equivalent range: 20/20–20/2000) and 661.1 ± 257.4 μm, respectively. The mean number of anti-VEGF injections administered was 5.6 ± 3.6. At the final examination, the mean logMAR BCVA and FT values were significantly improved relative to the baseline values (both P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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