Comparing Vitamin B12 and Nitrous Oxide Neurotoxicity in Operating Room Staff and other Hospital Staff: A Multicenter Study
| Autor: | Sahar Sadeghi, Afsaneh Nourozi, Hamidreza Azadi, Fardin Faraji, Mahsa Mardani, Bahman Sadeghi |
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| Jazyk: | English<br />Persian |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Journal of Mazandaran University of Medical Sciences, Vol 29, Iss 173, Pp 134-139 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1735-9260 1735-9279 |
| Popis: | Background and purpose: Nitrous oxide (N2O) is an anesthetic widely used in operating rooms. Chronic exposure to N2O causes decrease in mental performance, peripheral neuropathy, and polyneuropathy. The aim of this study was to compare neurological complications caused by N2O exposure between operating room staff and other hospital staff. Materials and methods: In this multicenter cohort study, operating room staff (n=110) and non-operating room staff (n= 224) in Arak Valiasr Hospital and Isfahan Al-zahra Hospital were randomly selected and individually matched. Both groups were examined for neuropathic symptoms and their medical history was recorded. Clinical neurological exams such as Romberg test were used in both groups. Patients with neuropathic sign and symptoms were referred to a neurology clinic to confirm any diagnosis. Results: The two groups were significantly different in ataxia, numbness, weakness and paresthesia of upper and lower limb, Romberg test score, and levels of Vitamin B12 (P |
| Databáze: | Directory of Open Access Journals |
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