The 31-nucleotide Y4-RNA fragment in plasma is a potential novel biomarker

Autor: Tatsuya Ishikawa, Arisa Haino, Mineaki Seki, Taro Kurihara, Takayuki Hirose, Yosuke Imai, Takuro Ishiguro, Takaaki Chou, Muneatsu Toshima, Hiroshi Terada, Masayuki Nashimoto
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Non-coding RNA Research, Vol 5, Iss 1, Pp 37-40 (2020)
Druh dokumentu: article
ISSN: 2468-0540
DOI: 10.1016/j.ncrna.2019.12.001
Popis: The 31- and 32-nt 5′-fragment of Y4-RNA (Y4RNAfr) exists abundantly in human peripheral blood plasma. Although physiological roles of the plasma Y4RNAfr are not well established, its potential utility as a diagnostic/prognostic marker for acute coronary syndrome was suggested. In this paper, to establish a normal range of the Y4RNAfr level in plasma, we measured plasma Y4RNAfr levels of 40 healthy persons using the method we have developed, and compared them with other blood test data. From the obtained data, we tentatively regarded
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