Effect of a brief alcohol counselling intervention on HIV viral suppression and alcohol use among persons with HIV and unhealthy alcohol use in Uganda and Kenya: a randomized controlled trial

Autor: Sarah B. Puryear, Florence Mwangwa, Fred Opel, Gabriel Chamie, Laura B. Balzer, Jane Kabami, James Ayieko, Asiphas Owaraganise, Elijah Kakande, George Agengo, Elizabeth Bukusi, Stella Kabageni, Daniel Omoding, Melanie Bacon, John Schrom, Sarah Woolf‐King, Maya L. Petersen, Diane V. Havlir, Moses Kamya, Judith A. Hahn
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of the International AIDS Society, Vol 26, Iss 12, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 1758-2652
09390243
DOI: 10.1002/jia2.26187
Popis: Abstract Introduction Unhealthy alcohol use significantly contributes to viral non‐suppression among persons with HIV (PWH). It is unknown whether brief behavioural interventions to reduce alcohol use can improve viral suppression among PWH with unhealthy alcohol use in sub‐Saharan Africa (SSA). Methods As part of the SEARCH study (NCT04810650), we conducted an individually randomized trial in Kenya and Uganda of a brief, skills‐based alcohol intervention among PWH with self‐reported unhealthy alcohol use (Alcohol Use Disorders Identification Test–Consumption [AUDIT‐C], prior 3 months, ≥3/female; ≥4/male) and at risk of viral non‐suppression, defined as either recent HIV viral non‐suppression (≥400 copies/ml), missed visits, out of care or new diagnosis. The intervention included baseline and 3‐month in‐person counselling sessions with interim booster phone calls every 3 weeks. The primary outcome was HIV viral suppression (200 ng/ml (RR 0.97, 95% CI: 0.92–1.02). Conclusions In a randomized trial of 401 PWH with unhealthy alcohol use and risk for viral non‐suppression, a brief alcohol intervention reduced unhealthy alcohol use but did not affect viral suppression at 24 weeks. Brief alcohol interventions have the potential to improve the health of PWH in SSA by reducing alcohol use, a significant driver of HIV‐associated co‐morbidities.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje