Hyperbaric Oxygen Therapy for Suburethral Vaginal Mucosal Necrosis after Interstitial Irradiation for Recurrent Cervical Cancer

Autor: Yoshihisa Arakaki, Yuko Shimoji, Tadaharu Nakasone, Yusuke Taira, Tomoko Nakamoto, Wataru Kudaka, Keiko Mekaru, Yoichi Aoki
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Obstetrics and Gynecology, Vol 2021 (2021)
Druh dokumentu: article
ISSN: 2090-6684
2090-6692
DOI: 10.1155/2021/1737975
Popis: Patients with gynecological malignancies can develop radiation injuries, such as cystitis, proctitis, and soft tissue necrosis which have approved indications for hyperbaric oxygen therapy (HBOT). A 76-year-old Japanese woman with vaginal recurrence of cervical cancer was treated with the high-dose rate interstitial brachytherapy. Twenty-one months after the irradiation, she developed radiation necrosis on the external urethral opening. Two cycles of HBOT were performed. HBOT consisted of delivering 100% oxygen for 60 minutes at 2.4 atmospheres absolute. Pressure exposure was performed once daily, 5 days a week for 6 weeks. Eventually, the necrotic mucosa was completely replaced by the normal mucosa. No adverse effects were observed. We successfully treated a case of late adverse events of radiation therapy with HBOT. It was noninvasive and appears to be a useful treatment option which should be considered standard treatment practice.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje