COMPARISON OF CONVENTIONAL RADIATIOTHERAPY AND ACCELERATED HYPERFRACTIONATED RADIATIOTHERAPY IN CHEMORADIATION TREATMENT FOR SMALL CELL LUNG CANCER

Autor:	I. A. Gulidov, A. G. Zolotkov, Yu. S. Mardynsky, I. N. Ivanova, L. V. Kursova, D. V. Gogolin, Yu. A. Ragulin
Jazyk:	ruština
Rok vydání:	2016
Předmět:	small cell lung cancer accelerated hyperfractionated radiotherapy chemoradiotherapy acute radiation-induced reactions Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Сибирский онкологический журнал, Vol 0, Iss 1, Pp 12-15 (2016)
Druh dokumentu:	article
ISSN:	1814-4861 2312-3168
Popis:	The 5-year treatment outcomes of 69 patients with stage IIA–IIIA locally advanced small cell lung cancer have been presented. Accelerated hyperfractionated radiotherapy was administered in the uneven daily dose fractionation (single dose of 1 + 1,5 Gy with a 5–6hour interval to a total dose of 60–70 Gy) depending on the health status and lung function. The complete response was achieved in 13 (42 %) patients, the median survival was 28 months and the 5-year survival rate was 26,2 %. Grade III lung and pericardium toxicities (according to RTOG toxicity scale) were observed in 3,2 % and 6,5 % of patients, respectively. No grade III–IV radiation-induced blood and esophageal damages were found.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5dc8559b8d90490183c6949f961ec475 Zobrazit plný text záznamu View record in DOAJ