Peripheral and lung resident memory T cell responses against SARS-CoV-2

Autor: Judith Grau-Expósito, Nerea Sánchez-Gaona, Núria Massana, Marina Suppi, Antonio Astorga-Gamaza, David Perea, Joel Rosado, Anna Falcó, Cristina Kirkegaard, Ariadna Torrella, Bibiana Planas, Jordi Navarro, Paula Suanzes, Daniel Álvarez-Sierra, Alfonso Ayora, Irene Sansano, Juliana Esperalba, Cristina Andrés, Andrés Antón, Santiago Ramón y Cajal, Benito Almirante, Ricardo Pujol-Borrell, Vicenç Falcó, Joaquín Burgos, María J. Buzón, Meritxell Genescà
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-23333-3
Popis: Lung resident memory T (TRM) cells are important for protection from viral infection in the lungs. Here the authors use paired lung biopsy material and blood to characterize T cell responses in patients with COVID-19 over time and find persistence of antiviral lung TRM cells that might be important to limit reinfection.
Databáze: Directory of Open Access Journals