Undifferentiated nasopharyngeal cancer extending to maxillary sinus: a case report

Autor: Mohamed Beghdad, Amine Mkhatri, Yassine Harmoumi, Meriem Doumiri, Sami Rouadi, Reda Abada, Mohamed Roubal, El Benna Naima, Mohamed Mahtar
Jazyk: English<br />French
Rok vydání: 2020
Předmět:
Zdroj: The Pan African Medical Journal, Vol 36, Iss 276 (2020)
Druh dokumentu: article
ISSN: 1937-8688
DOI: 10.11604/pamj.2020.36.276.24766
Popis: Undifferentiated nasopharyngeal cancer of the cavum (UCNT) is the most frequent neoplasm of the nasopharynx, having a close relationship with exposure to Epstein-Barr virus. It has a high potential for locoregional or distant invasion which are the cause of some treatment failures. The extension to the maxillary sinus is rarely described. We report here the case of a 38-year-old patient with headaches associated with epistaxis, left otalgia and facial pain. Examination by anterior rhinoscopy objectively revealed a polylobed ulcerating mass. Otoscopic examination revealed a left seromucous otitis media. Computed tomography showed a voluminous tumour process in the infra temporal fossa and nasopharynx with significant locoregional extension particularly in the maxillary sinus. Pathological examination revealed an UCNT of the cavum and the patient was classified as T4N2M0. The patient received chemoradiotherapy, with wide irradiation of the cervical lymph node areas. The deep localization of the cancer of the cavum, which is difficult to examine, requires a diagnostic and extension work-up, both endoscopic and radiological, which is an important step in the diagnostic and therapeutic management.
Databáze: Directory of Open Access Journals