| Autor: |
D. Hagiwara, K. Sato, M. Miyazaki, M. Kamada, N. Moriwaki, T. Nakano, S. Shiotsuka, C. Tokushige, H. Toh, H. Kamimura, A. Togawa, T. Takata |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
International Journal of Infectious Diseases, Vol 77, Iss , Pp 34-39 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2018.09.025 |
| Popis: |
Objective: The objective of this study was to evaluate the effects of earlier intervention by an antimicrobial stewardship team (AST) on antimicrobial use, antimicrobial resistance rates, and the clinical outcomes, without changing the weekly intervention schedule. Methods: A retrospective study was conducted at Fukuoka University Hospital between April 2013 and March 2016. The effects were compared among three study periods (SP): SP1 (patients receiving anti-methicillin-resistant Staphylococcus aureus agents and carbapenems for ≥14 days), SP2 (patients receiving specific antimicrobials for ≥14 days), and SP3 (patients receiving specific antimicrobials regardless of the duration of treatment). Results: The timing of AST intervention was shortened from an average of 15.5 days after administration in SP1 to 4.2 days in SP3. The antimicrobial use density (AUD) of carbapenems and piperacillin–tazobactam decreased significantly (SP2 vs. SP3, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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