Contemporary use and outcomes of radiation and chemotherapy for unresectable pancreatic cancer

Autor: Shalini Moningi, Xiudong Lei, Penny Fang, Cullen M. Taniguchi, Emma B. Holliday, Eugene J. Koay, Albert C. Koong, Ethan B. Ludmir, Bruce D. Minsky, Prajnan Das, Sharon H. Giordano, Grace L. Smith
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Clinical and Translational Radiation Oncology, Vol 35, Iss , Pp 9-16 (2022)
Druh dokumentu: article
ISSN: 2405-6308
DOI: 10.1016/j.ctro.2022.04.007
Popis: Background: We assessed radiation treatment (RT) use and complications for unresectable pancreatic cancer in the US, comparing conventionally fractionated (CFRT) and stereotactic body radiation treatment (SBRT) to inform real-world expected outcomes and practice. Material and Methods: We analyzed 5,624 patients with non-metastatic, unresectable pancreatic cancer (2,522 older patients age > 65, diagnosed 2006–2013 in Medicare linked data; and 3,102 younger patients age 0.05, all comparisons). Among older patients, increased complications were seen for SBRT in 1–4 fractions vs. CFRT (P
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