Outcome of radiosurgery treatment with a linear accelerator in patients with trigeminal neuralgia

Autor: N. Cordero Tous, J. de la Cruz Sabido, A.M. Román Cutillas, E.J. Saura Rojas, A.M. Jorques Infante, G. Olivares Granados
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Neurología (English Edition), Vol 32, Iss 3, Pp 166-174 (2017)
Druh dokumentu: article
ISSN: 2173-5808
DOI: 10.1016/j.nrleng.2015.10.001
Popis: Introduction: An overview of the effectiveness of radiosurgery in patients diagnosed with trigeminal neuralgia with an analysis of potential predictors of good outcome. Methods: All patients treated with linear accelerator radiosurgery between 2004 and 2011 were analysed. A dose of 60 Gy dose was administered 1 to 2 mm from the root entry zone with a maximum isodose of 20% delivered to the brainstem. Clinical results for pain control and any side effects were analysed at 12 and 36 months (BNI score). Results: The study included 71 patients (mean follow-up 50.5 months). Pain improvement at 12 months was observed in 68.11% of the total (28.98% with BNI score I–II; 39.12% with BNI score III) and at 36 months in 58.21% (23.88% BNI score I–II; 34.32% BNI score III). Average recovery time was 3.69 months and the relapse rate was 44.68%. Patients with typical pain displayed statistically significant differences in improvement rates at 12 and at 36 months (P
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