Histological transitional zone pull-through in Hirschsprung disease. Postoperative functional results and current recommendations

Autor: Luis De-la Torre, Alfredo Domínguez, Michael Arnold, Mark Lovell, Diego Martínez, Andrea Bischoff, Lea Wehrli
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2023
Předmět:
Zdroj: Boletín Médico del Hospital Infantil de México, Vol 80, Iss 6 (2023)
Druh dokumentu: article
ISSN: 0539-6115
DOI: 10.24875/BMHIM.23000050
Popis: Background: Surgeons create a neorectum to repair patients with Hirschsprung’s disease (HD), which should be formed from a normoganglionic bowel. However, the neorectum is occasionally created with a transition zone (TZ) bowel. A neorectum created with a TZ has been postulated as a cause of postoperative enterocolitis or constipation. This study compares the incidence of enterocolitis and constipation in patients with TZ neorectum and normoganglionic bowel. Methods: We conducted a retrospective review of patients with rectosigmoid HD who underwent primary pull-through. Patients were divided into normoganglionic neorectum (NNR) and TZ neorectum. The diagnosis was based on the final histopathologic report of the proximal margin. The incidence of enterocolitis and constipation was compared between these two groups. Results: A total of 98 HD patients were analyzed. Seventy-one patients fulfilled the inclusion criteria. 65 (92%) had a NNR, and six patients (8%) had a TZ neorectum. From these patients, 42 (59%) presented with enterocolitis or constipation. However, there was no significant difference between both groups. Conclusion: The present study showed no difference in the incidence of enterocolitis or postoperative constipation in HD patients with normoganglionic or TZ neorectum. These results suggest that TZ neorectum does not cause postoperative obstructive symptoms.
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