New full-substituted cyclopropanes derived from the one-pot reaction of Meldrum’s acid with aldehydes and BrCN in the presence of Et3N

Autor: Nader Noroozi Pesyan, Ali Gharib, Mohammad Behroozi, Alireza Shokr
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Arabian Journal of Chemistry, Vol 10, Iss S2, Pp S1558-S1566 (2017)
Druh dokumentu: article
ISSN: 1878-5352
DOI: 10.1016/j.arabjc.2013.05.024
Popis: Reaction of 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum’s acid) with various aldehydes in the presence of cyanogen bromide and triethylamine leads to the selective and efficient formation of full-substituted cyclopropanes at room temperature. The products were obtained in good to excellent yields. Structure elucidation is carried out by 1H, 13C NMR, FT-IR spectroscopy and mass analysis techniques. A possible mechanism for the formation is discussed.
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