Autor: |
Loris Wauthier, Julien Favresse, Michaël Hardy, Jonathan Douxfils, Grégoire Le Gal, Pierre-Marie Roy, Nick van Es, Cihan Ay, Hugo ten Cate, Thierry Vander Borght, Michaël V. Dupont, Thomas Lecompte, Giuseppe Lippi, François Mullier |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Diagnostics, Vol 12, Iss 11, p 2770 (2022) |
Druh dokumentu: |
article |
ISSN: |
2075-4418 |
DOI: |
10.3390/diagnostics12112770 |
Popis: |
D-dimer is a multifaceted biomarker of concomitant activation of coagulation and fibrinolysis, which is routinely used for ruling out pulmonary embolism (PE) and/or deep vein thrombosis (DVT) combined with a clinical pretest probability assessment. The intended use of the tests depends largely on the assay used, and local guidance should be applied. D-dimer testing may suffer from diagnostic errors occurring throughout the pre-analytical, analytical, and post-analytical phases of the testing process. This review aims to provide an overview of D-dimer testing and its value in diagnosing PE and discusses the variables that may impact the quality of its laboratory assessment. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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