Serum monoterpene levels, glucose homeostasis, lipid profiles, and metabolic syndrome in adults: NHANES, 2013–2014

Autor: Wei-Jie Wang, Yu-Ling Lin, Chikang Wang, Chien-Yu Lin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Emerging Contaminants, Vol 10, Iss 2, Pp 100281- (2024)
Druh dokumentu: article
ISSN: 2405-6650
DOI: 10.1016/j.emcon.2023.100281
Popis: Monoterpenes are organic compounds which have been studied for their medicinal benefits. However, the association between monoterpene exposure and metabolic parameters in humans is unknown. We investigated the connection between three specific monoterpenes (α-pinene, β-pinene, and limonene), glucose homeostasis biomarkers, lipid profiles, and metabolic syndrome (MS) in 1627 adults from the National Health and Nutrition Examination Survey (NHANES) 2013–2014. We found serum levels of α-pinene and β-pinene were positively associated with fasting glucose, total cholesterol, triglyceride, and apolipoprotein B. In addition, increased levels of limonene and Σmonoterpene (sum of three monoterpene chemicals) were linked to higher insulin, β-cell function, total cholesterol, low density lipoprotein cholesterol (LDL-C), triglycerides, and apolipoprotein B. Participants with all three monoterpenes above the 50th percentile had notably higher values for total cholesterol and triglycerides compared to those with all three monoterpenes below the 50th percentile (P for trend
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