| Autor: |
Miyuki Onishi, Mitsuru Ohishi, Takashi Takagi, Yuji Tatara, Nozomi Kato, Hiromi Rakugi |
| Jazyk: |
angličtina |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Artery Research, Vol 3, Iss 3 (2009) |
| Druh dokumentu: |
article |
| ISSN: |
1876-4401 |
| DOI: |
10.1016/j.artres.2009.06.018 |
| Popis: |
Background: Many reports have shown that brachial-ankle pulse wave velocity (baPWV) has an effect on evaluation of atherosclerotic change and would be one of the prognostic factors for hypertension (HT). It has been reported that chronic kidney disease (CKD) would influence the prognosis of HT or diabetes mellitus. Therefore we examined how baPWV and CKD effects the incidence of cardiovascular disease (CVD) by the cohort study in hypertensive patients using the AT-form which we can measure PWV easily. Methods: This study included 380 patients with essential HT (male/female 206/174, mean age 60.9±12.1, mean follow period 41months) whose baPWV could be measured from October, 2000 to December, 2004. We set up stroke (n=19) and CVD (n=18) as a primary end point by the questionnaire. We estimated CKD as lower glomerular filtration rate (GFR) with MDRD formula and proteinuria. We produced quartile groups according to the baseline measurements of baPWV or the presence of CKD and assessed the prognostic impact on stroke and CVD. Results: There was a significant negative correlation between baPWV and GFR (P |
| Databáze: |
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| Externí odkaz: |
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