Synthetic biology of microbes synthesizing polyhydroxyalkanoates (PHA)

Autor: Guo-Qiang Chen, Xiao-Ran Jiang, Yingying Guo
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Synthetic and Systems Biotechnology, Vol 1, Iss 4, Pp 236-242 (2016)
Druh dokumentu: article
ISSN: 2405-805X
DOI: 10.1016/j.synbio.2016.09.006
Popis: Microbial polyhydroxyalkanoates (PHA) have been produced as bioplastics for various purposes. Under the support of China National Basic Research 973 Project, we developed synthetic biology methods to diversify the PHA structures into homo-, random, block polymers with improved properties to better meet various application requirements. At the same time, various pathways were assembled to produce various PHA from glucose as a simple carbon source. At the end, Halomonas bacteria were reconstructed to produce PHA in changing morphology for low cost production under unsterile and continuous conditions. The synthetic biology will advance the PHA into a bio- and material industry.
Databáze: Directory of Open Access Journals