Qualitative and Quantitative Analyses of the Enantiomers of Nicotine and Related Alkaloids Employing Chiral Supercritical Fluid Chromatography in Commercial Nicotine Samples and in E-Cigarette Products

Autor: Perfetti T.A., Ashraf-Khorassani M., Coleman W.M., Dube M.F.
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Contributions to Tobacco and Nicotine Research, Vol 32, Iss 3, Pp 77-89 (2023)
Druh dokumentu: article
ISSN: 2719-9509
DOI: 10.2478/cttr-2023-0010
Popis: Several commercial sources of tobacco-derived nicotine (TDN) and synthetic nicotine (SyN) and a variety of e-cigarette liquids employing either TDN or SyN have been evaluated to determine the enantiomer distributions of R- and S-nicotine and R- and S-nornicotine by chiral supercritical fluid chromatography (chiral-SFC) with UV diode array detection (DAD-UV). The data generated are used to test the mismatched vs. matched hypothesis of Cheetham et al. as a means to distinguish products containing TDN from products with SyN.
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