In vivo imaging of invasive aspergillosis with 18F-fluorodeoxysorbitol positron emission tomography

Autor: Dong-Yeon Kim, Ayoung Pyo, Sehyeon Ji, Sung-Hwan You, Seong Eun Kim, Daejin Lim, Heejung Kim, Kyung-Hwa Lee, Se-Jeong Oh, Ye-rim Jung, Uh Jin Kim, Subin Jeon, Seong Young Kwon, Sae-Ryung Kang, Hyang Burm Lee, Hoon Hyun, So-Young Kim, Kyung-Sub Moon, Sunwoo Lee, Seung Ji Kang, Jung-Joon Min
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-29553-5
Popis: Current diagnostic methods for invasive aspergillosis are time-consuming and poorly sensitive. Here, the authors show that positron emission tomography with 2-deoxy-2-18F-fluorosorbitol can visualize Aspergillus fumigatus infection of the lungs, brain and muscles in mouse models, and can distinguish pulmonary aspergillosis from other diseases such as Staphylococcus aureus infection and lung cancer.
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