КЛИНИЧЕСКОЕ ТЕЧЕНИЕ И ИСХОДЫ ХРОНИЧЕСКОЙ ДЕЛЬТА-ИНФЕКЦИИ В ЭНДЕМИЧНОМ РЕГИОНЕ
| Autor: | Л. Ю. Ильченко, Т. В. Кожанова, А. А. Сарыглар, Я.-Н. Д. Сонам-Байыр, О. Н. Сарыг-Хаа, Р. М. Соян, Ю. П. Зубков, О. В. Исаева, К. К. Кюрегян, М. И. Михайлов |
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| Jazyk: | ruština |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Архивъ внутренней медицины, Vol 0, Iss 5, Pp 51-56 (2012) |
| Druh dokumentu: | article |
| ISSN: | 2226-6704 2411-6564 |
| DOI: | 10.20514/2226-6704-2012-0-5-51-56 |
| Popis: | Total 214 patients with delta infection were examined. Total 48 patients were followed annually during the observation period (2009–2011). Diagnosis of chronic hepatitis delta (CHD) was established in 78,6% (162/206) cases, liver cirrhosis (LC) — in 21,4% (44/206). HDV RNA was detected in 26,2% (56/214) patients. HDV was genotype I. Progression of CL was observed among 31,3% (15/48) of followed patients, decompensation of CL — in 8,3% (4/48), hepatocellular carcinoma — in 4,2% (2/48) cases; mortality was 29,2% (14/48), with hepatic coma and bleeding from esophageal varices as the main cause of death. |
| Databáze: | Directory of Open Access Journals |
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