| Autor: |
Mrigendra Rajput, Tooba Momin, Amit Singh, Surya Banerjee, Andrew Villasenor, Jessica Sheldon, Pratikshya Paudel, Ravindra Rajput |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Veterinary and Animal Science, Vol 19, Iss , Pp 100279- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2451-943X |
| DOI: |
10.1016/j.vas.2022.100279 |
| Popis: |
Immunoglobulin A (IgA) is one of the important and most abundant immunoglobulins which neutralize invading pathogens at mucosal sites. Gut microbial community and their metabolites which are responsible for higher IgA are poorly known. The current study was carried out to determine those microbial community and their metabolites. Twenty-two healthy, 26 days wean piglets were used in the study. After 10 days of weaning, piglets were divided into two groups. Group 1 with significantly higher fecal IgA while group 2 with significantly lower IgA concentrations from each other. Both groups were analyzed for the fecal inflammatory cytokine, fecal microbial community using 16S ribosomal sequencing, and microbial metabolites using GC–MS.Results showed that Firmicutes and Bacteroidetes constituted 90.56% of the microbiome population in the fecal matter of pigs with higher IgA concentration while pigs with lower fecal IgA had Firmicutes and Bacteroidetes abundance as of 95.56%. Pigs with higher IgA had significantly higher Bacteroidota and Desulfobacterota populations, while significantly lower Firmicutes and Firmicutes/ Bacteroidota ratio (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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