Efficacy of antibiotic therapy in urogenous reactive arthritis and peripheral variant of ankylosing spondyloarthritis

Autor: M M Urumova, E R Agababova, S. I. Soldatova, S V Shubin
Jazyk: ruština
Rok vydání: 2003
Předmět:
Zdroj: Научно-практическая ревматология, Vol 41, Iss 4, Pp 49-52 (2003)
Druh dokumentu: article
ISSN: 1995-4484
1995-4492
DOI: 10.14412/1995-4484-2003-1333
Popis: Objective. To study efficacy of antibiotics from two different groups - asitromycin/sumamed (macrolid) and lomefloxacine/maxaquine (ftorquinolone) in urogenous rheactive arthritis (URA) and peripheral variant of ankylosing spondyloarthritis (PVAS) with signs of urogenital Chlamidia inflammation. Material and methods. 86 pts were examined: 51 with URA (including Reiter’s disease - RD) and 35 with PVAS. Diagnoses of URA, RD and PVAS were definite in all pts. 43 pts received sumamed in total dose of I5g, 43 - maxaquinum - 24g total. Treatment efficacy was assessed according to clinical and laboratory indices changes immediately after the end of treatment and then in 1 and 3 months. Results. Similar significant decrease of swollen and tender joint counf as well as laboratory activity indices accompanied by disappearance of urogenital inflammation signs was seen in URA and PVAS. Conclusion. Antibiotics administration for chlamidiosis is indicated in all cases of URA and PVAS with urogenital inflammation signs.
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