Recurrent Hypertriglyceridemia-Induced Pancreatitis due to Multifactorial Chylomicronemia Syndrome in a Patient With Ketosis-Prone Diabetes Mellitus
| Autor: | Thewjitcharoen Yotsapon, Komindr Surat, Veerasomboonsin Veekij, Wattanawiroon Kewalin, Nakasatien Soontaree, Krittiyawong Sirinate, Himathongkam Thep |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Clinical Medicine Insights: Case Reports, Vol 15 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1179-5476 11795476 |
| DOI: | 10.1177/11795476221119445 |
| Popis: | The triad of diabetic ketoacidosis (DKA), severe hypertriglyceridemia, and acute pancreatitis have been occasionally described in severely obese patients with type 2 diabetes mellitus (T2DM). Herein, we present a long-term clinical course of a Thai man with ketosis-prone diabetes mellitus (KPDM) complicated with recurrent pancreatitis due to multifactorial chylomicronemia syndrome. Genetic testing showed no mutation in lipoprotein lipase (LPL) and its co-factors. The patient was referred to multidisciplinary team for lifelong weight loss consultation, limiting intake of fat and simple carbohydrates, and adherence to lipid-lowering medications. Subsequent follow-up 1 year later showed no recurrent pancreatitis. In patients with multifactorial chylomicronemia syndrome, long-term management with dietary modifications together with pharmacotherapy remains the cornerstone of successful treatment. |
| Databáze: | Directory of Open Access Journals |
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