What risk of death would people take to be cured of HIV and why? A survey of people living with HIV

Autor: Benjamin R. Murray, Allison Kratka, Karen A. Scherr, Nir Eyal, Jennifer Blumenthal-Barby, Kenneth A. Freedberg, Daniel R. Kuritzkes, James K. Hammitt, Regina Edifor, Madelaine N. Katz, Kathryn I. Pollak, Brian J. Zikmund-Fisher, Scott D. Halpern, Mary C. Barks, Peter A. Ubel
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Virus Eradication, Vol 5, Iss 2, Pp 109-115 (2019)
Druh dokumentu: article
ISSN: 2055-6640
DOI: 10.1016/S2055-6640(20)30052-2
Popis: People living with HIV (PLWHIV) can reasonably expect near-normal longevity, yet many express a willingness to assume significant risks to be cured. We surveyed 200 PLWHIV who were stable on antiretroviral therapy (ART) to quantify associations between the benefits they anticipate from a cure and their risk tolerance for curative treatments. Sixty-five per cent expected their health to improve if cured of HIV, 41% predicted the virus would stop responding to medications over the next 20 years and 54% predicted experiencing serious medication side effects in the next 20 years. Respondents’ willingness to risk death for a cure varied widely (median 10%, 75th percentile 50%). In multivariate analyses, willingness to risk death was associated with expected long-term side effects of ART, greater financial resources and being employed (all P
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