Epstein-Barr virus (EBV) frequency in tissue samples of women with breast cancer in Mashhad, Iran
| Autor: | Ahmad Tafaghod, Samaneh Sajjadi, Mohammadhossein Taherynejad, Hassan Mehrad- Majd, Sahar Ravanshad |
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| Jazyk: | perština |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, Vol 26, Iss 12, Pp 30-38 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1680-2993 2008-2363 |
| DOI: | 10.22038/ijogi.2024.77354.5965 |
| Popis: | Introduction: Breast cancer is one of the most common cancers in the world that its incidence rate has increased over the last decade. Although the causes and risk factors of breast cancer are not fully known, studies have been reported on the relationship between breast cancer and viral agents, including the Epstein-Barr virus (EBV). Therefore, the present study was performed with aim to explore the correlation between EBV and breast cancer. Methods: In this cross-sectional study which was conducted using breast tissue pathology samples collected from Mashhad hospitals between 2017 and 2022, 30 paraffin tissue samples from breast cancer patients and 33 paraffin tissue samples as a control group from benign breast diseases were collected. After the DNA extraction processes, the EBV virus was tested by polymerase chain reaction (PCR). Data analysis was done using SPSS software (version 20) and Chi-square, Fisher's exact and t-test. P |
| Databáze: | Directory of Open Access Journals |
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