Sleep, Melatonin, and the Menopausal Transition: What Are the Links?

Autor:	Shazia Jehan, Giardin Jean-Louis, Ferdinand Zizi, Evan Auguste, Seitikurippu R. Pandi-Perumal, Ravi Gupta, Hrayr Attarian, Samy I. McFarlane, Rüdiger Hardeland, Amnon Brzezinski
Jazyk:	angličtina
Předmět:	Sleep Melatonin Aging Circadian rhythm Hormones Gender Menopause Psychology BF1-990 Consciousness. Cognition BF309-499
Zdroj:	Sleep Science, Vol 10, Iss 1, Pp 11-18
Druh dokumentu:	article
ISSN:	1984-0659 1984-0063
DOI:	10.5935/1984-0063.20170003
Popis:	The pineal hormone Melatonin plays an important role in the regulation of the circadian sleep/wake cycle, mood, and perhaps immune functions, carcinogensis and reproduction. The human circadian rhythm of melatonin release from the pineal gland is tightly synchronized with the habitual hours of sleep. Peri- and postmenopausal women often complain of difficulties initiating and/or maintaining sleep, with frequent nocturnal and early morning awakenings. In this review we discuss the pathophysiology of melatonin function as it relates to sleep disorders in menopausal women, highlighting the potential use of exogenous melatonin during the menopausal transition and beyond.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d5cdb95adbc148d3a9cd056a17b187f3 Zobrazit plný text záznamu View record in DOAJ