Increased Production of Outer Membrane Vesicles by Salmonella Interferes with Complement-Mediated Innate Immune Attack

Autor: Ruchika Dehinwal, Danielle Cooley, Alexey V. Rakov, Akhil S. Alugupalli, Joey Harmon, Olivier Cunrath, Prashanth Vallabhajosyula, Dirk Bumann, Dieter M. Schifferli
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mBio, Vol 12, Iss 3 (2021)
Druh dokumentu: article
ISSN: 2150-7511
DOI: 10.1128/mBio.00869-21
Popis: Bacterial outer membrane vesicles (OMVs) mediate critical bacterium-bacterium and host-microbial interactions that influence pathogenesis through multiple mechanisms, including the elicitation of inflammatory responses, delivery of virulence factors, and enhancement of biofilm formation. As such, there is a growing interest in understanding the underlying mechanisms of OMV production.
Databáze: Directory of Open Access Journals