Definite therapy of mixed infection alleviates refractory dilemma of adult chronic suppurative otitis media

Autor: Chih-Hao Chen, Ching-Yuan Wang, Meng-Yu Cheng, Wen-Hsin Hsih, Ni Tien, Chia-Huei Chou, Po-Chang Lin, Chih-Yu Chi, Mao-Wang Ho, Min-Chi Lu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Microbiology, Immunology and Infection, Vol 55, Iss 6, Pp 1283-1292 (2022)
Druh dokumentu: article
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2022.07.014
Popis: The characteristics, risk factors, microbial distributions and effective treatment regimens for Chronic suppurative otitis media (CSOM) patients intractable to empirical therapy were analyzed.Adult CSOM patients of China Medical University Hospital from 2018 to 2020 were included. Subjects of refractory and non-refractory groups were investigated for characteristics of age, sex, nation, comorbidities, otomycosis, and associated complications. Risk factors, microbiology distributions, and treatment regimens were analyzed.Twenty-six refractory patients (55.0 ± 17.7 years) and 66 non-refractory patients (54.1 ± 13.7 years) were studied. A significantly higher rate of otomycosis and CSOM complications was observed in refractory group than in non-refractory one (73.1% vs. 36.4%; p = 0.002; 57.7% vs. 10.6%, p
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