RELATION OF DISTURBANCES IN THE ERYTHROCYTES ELECTRICAL ACTIVITY WITH DYSLIPIDEMIA IN THE METABOLIC SYNDROME
| Autor: | V. I. Podzolkov, T. V. Koroleva, A. E. Bragina, M. G. Kudryavtseva, G. I. Bragina, M. V. Pisarev |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Рациональная фармакотерапия в кардиологии, Vol 14, Iss 3, Pp 344-349 (2018) |
| Druh dokumentu: | article |
| ISSN: | 1819-6446 2225-3653 |
| DOI: | 10.20996/1819-6446-2018-14-3-344-349 |
| Popis: | Aim. To study the erythrocyte electric charge (EEC) in patients with metabolic syndrome (MS).Material and methods. 112 patients (mean age 61.4±7.2 years) with MS (average duration of MS 8.7±5.2 years) were examined. Control group consisted of healthy volunteers (n=25) of similar age. The level of EEC was detected by the method of adsorption of a positive cationic dye (cationic blue O) on the surface of the erythrocyte plasma membrane up to the complete neutralization of their negative charge, followed by photometry of the solution and calculation of the number of charges on the erythrocyte cell surface. The results of the study were processed by Statistica 10.0 software.Results. Hypertension was found in 73% of patients with MS, hyperglycemia – in 39%, diabetes – in 36%, dyslipidemia – in 80% of patients. The EEC in MS patients (1.59±0.05×107) was lower than this in the control group (1.65±0.03×107; p |
| Databáze: | Directory of Open Access Journals |
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