Comparison of Fourier-Domain and Time-Domain Optical Coherence Tomography in the Measurement of Thinnest Corneal Thickness in Keratoconus

Autor: Chunxiao Wang, Xueying Xia, Bishan Tian, Shiyou Zhou
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Ophthalmology, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 2090-004X
2090-0058
DOI: 10.1155/2015/402925
Popis: Objective. To compare fourier-domain optical coherence tomography (FD-OCT) and time-domain OCT (TD-OCT) in the determination of thinnest corneal thickness (TCT). Methods. This study included 55 keratoconus patients and 50 healthy volunteers. The RTVue-OCT (FD-OCT) and Visante-OCT (TD-OCT) were used for the measurement of the TCT. Three consecutive scans were performed. The comparison and agreement between the two modalities were analyzed by paired t-test, the Pearson correlation, intraclass correlation coefficient (ICC), and Bland-Altman plots. intraobserver repeatability was analyzed by the intraobserver within-subject standard deviation (S(w)), coefficient of variation (CV(w)), and ICC. Results. The TCT value of normal corneas was higher by RTVue-OCT (530.4 ± 19.7 μm) than Visante-OCT (521.5 ± 18.3 μm) (p
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