Promising Antimicrobial Properties of Bioactive Compounds from Different Honeybee Products

Autor: Magdalena Ratajczak, Dorota Kaminska, Eliza Matuszewska, Elżbieta Hołderna-Kedzia, Jarosław Rogacki, Jan Matysiak
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Molecules, Vol 26, Iss 13, p 4007 (2021)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules26134007
Popis: Bee products have been known for centuries for their versatile healing properties. In recent decades they have become the subject of documented scientific research. This review aims to present and compare the impact of bee products and their components as antimicrobial agents. Honey, propolis, royal jelly and bee venom are bee products that have antibacterial properties. Sensitivity of bacteria to these products varies considerably between products and varieties of the same product depending on their origin. According to the type of bee product, different degrees of activity were observed against Gram-positive and Gram-negative bacteria, yeasts, molds and dermatophytes, as well as biofilm-forming microorganisms. Pseudomonas aeruginosa turned out to be the most resistant to bee products. An analysis of average minimum inhibitory concentration values for bee products showed that bee venom has the strongest bacterial effectiveness, while royal jelly showed the weakest antibacterial activity. The most challenging problems associated with using bee products for medical purposes are dosage and safety. The complexity and variability in composition of these products raise the need for their standardization before safe and predictable clinical uses can be achieved.
Databáze: Directory of Open Access Journals
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