The Effects of 6 Weeks of Endurance Training and Consumption of Different Doses of Boldenone on Hematological Factors and Spleen Structure Changes in Male Wistar Rats
Autor: | Asieh Abbassi Daloii, Seyed Javad Ziaolhagh, Mojde Fazelniya |
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Jazyk: | perština |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, Vol 11, Iss 4, Pp 20-31 (2017) |
Druh dokumentu: | article |
ISSN: | 1735-7799 2008-1375 |
Popis: | Background and Objectives: Regardless of how many periods and how long the androgenic-anabolic steroids have been used, they can cause side effects. The objective of this study was to investigate the effect a 6-week endurance training and using different doses of anabolic steroid boldenone on hematological factors and changes in spleen structure in male Wistar rats. Methods: In this experimental study, 47 male Wistar rats aged 12 weeks, were randomly divided into 7 groups (control, sham, boldenone-1, boldenone-2, endurance training, endurance training+boldenone-1, endurance training+boldenone-2). Increasing endurance training program was performed at the speed of 10-30m/min (Vo2max, 75-80%) for 6 weeks and 5 days/week. The drug was injected deeply into the quadriceps and hamstring muscles once a week, on an appointed day. After anesthesia and dissection, the spleen was removed. Finally, the selected microscopic sections, were studied using a light microscope after staining with hematoxylin and eosin. Data were analyzed by dependent t-, one-way ANOVA, and post-hoc LSD tests at α |
Databáze: | Directory of Open Access Journals |
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