The Effects of 6 Weeks of Endurance Training and Consumption of Different Doses of Boldenone on Hematological Factors and Spleen Structure Changes in Male Wistar Rats

Autor: Asieh Abbassi Daloii, Seyed Javad Ziaolhagh, Mojde Fazelniya
Jazyk: perština
Rok vydání: 2017
Předmět:
Zdroj: Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, Vol 11, Iss 4, Pp 20-31 (2017)
Druh dokumentu: article
ISSN: 1735-7799
2008-1375
Popis: Background and Objectives: Regardless of how many periods and how long the androgenic-anabolic steroids have been used, they can cause side effects. The objective of this study was to investigate the effect a 6-week endurance training and using different doses of anabolic steroid boldenone on hematological factors and changes in spleen structure in male Wistar rats. Methods: In this experimental study, 47 male Wistar rats aged 12 weeks, were randomly divided into 7 groups (control, sham, boldenone-1, boldenone-2, endurance training, endurance training+boldenone-1, endurance training+boldenone-2). Increasing endurance training program was performed at the speed of 10-30m/min (Vo2max, 75-80%) for 6 weeks and 5 days/week. The drug was injected deeply into the quadriceps and hamstring muscles once a week, on an appointed day. After anesthesia and dissection, the spleen was removed. Finally, the selected microscopic sections, were studied using a light microscope after staining with hematoxylin and eosin. Data were analyzed by dependent t-, one-way ANOVA, and post-hoc LSD tests at α
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