| Autor: |
Roxana Ghiulai, Oana Janina Roşca, Diana Simona Antal, Marius Mioc, Alexandra Mioc, Roxana Racoviceanu, Ioana Macaşoi, Tudor Olariu, Cristina Dehelean, Octavian Marius Creţu, Mirela Voicu, Codruţa Şoica |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Molecules, Vol 25, Iss 23, p 5557 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules25235557 |
| Popis: |
Wounds are among the most common skin conditions, displaying a large etiological diversity and being characterized by different degrees of severity. Wound healing is a complex process that involves multiple steps such as inflammation, proliferation and maturation and ends with scar formation. Since ancient times, a widely used option for treating skin wounds are plant- based treatments which currently have become the subject of modern pharmaceutical formulations. Triterpenes with tetracyclic and pentacyclic structure are extensively studied for their implication in wound healing as well as to determine their molecular mechanisms of action. The current review aims to summarize the main results of in vitro, in vivo and clinical studies conducted on lupane, ursane, oleanane, dammarane, lanostane and cycloartane type triterpenes as potential wound healing treatments. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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