Botulinum toxin: Non cosmetic and off-label dermatological uses

Autor: Ali S. Al-Ghamdi, Noah Alghanemy, Hanan Joharji, Dhafer Al-Qahtani, Hasan Alghamdi
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Dermatology and Dermatologic Surgery, Vol 19, Iss 1, Pp 1-8 (2015)
Druh dokumentu: article
ISSN: 2352-2410
DOI: 10.1016/j.jdds.2014.06.002
Popis: Botulinum toxin (BT-A) is a neurotoxin which is produced by the Gram-positive anaerobic bacterium Clostridium botulinum. The efficacy of Botulinum toxin in treating hyperhidrosis and the glabellar lines is well known and FDA approved. Because BT-A inhibits the release of acetylcholine and many other neurotransmitters such as norepinephrine and substance P at the level of nerve ending, this toxin has been used to treat a lot of dermatological disorders which are thought to be triggered by these neurotransmitters. In this article we are discussing the medical off-label uses of BT-A in dermatology.
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