| Autor: |
Vadim B. Krylov, Arsenii S. Solovev, Ilya A. Puchkin, Dmitry V. Yashunsky, Anna V. Antonets, Olga Y. Kutsevalova, Nikolay E. Nifantiev |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of Fungi, Vol 7, Iss 7, p 504 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2309-608X |
| DOI: |
10.3390/jof7070504 |
| Popis: |
Monoclonal antibody EBCA-1 is used in the sandwich immune assay for the detection of circulating Candida mannan in blood sera samples for the diagnosis of invasive candidiasis. To reinvestigate carbohydrate specificity of EBCA-1, a panel of biotinylated oligosaccharides structurally related to distinct fragments of Candida mannan were loaded onto a streptavidin-coated plate to form a glycoarray. Its use demonstrated that EBCA-1 recognizes the trisaccharide β-Man-(1→2)-α-Man-(1→2)-α-Man and not homo-α-(1→2)-linked pentamannoside, as was reported previously. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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