Risk factors for nosocomial infection in a Brazilian neonatal intensive care unit

Autor: Ana Carolina Vieira Costa Fernandes Távora, Antonieta B. Castro, Maria Afonsina M. Militão, José Eduilton Girão, Karina de Cássia Braga Ribeiro, Lara Gurgel Fernandes Távora
Jazyk: angličtina
Předmět:
Zdroj: Brazilian Journal of Infectious Diseases, Vol 12, Iss 1, Pp 75-79
Druh dokumentu: article
ISSN: 1678-4391
1413-8670
DOI: 10.1590/S1413-86702008000100016
Popis: This study was designed to describe the epidemiology and risk factors for nosocomial infection (NI) in a Brazilian neonatal intensive care unit (NICU). This study was a retrospective cohort from January to December, 2003. All neonates admitted to the NICU. Infection surveillance was conducted according to the NNIS, CDC. Chi-square test and logistic regression model were performed for statistical analyses. The study was conducted at a public, tertiary referral NICU of a teaching hospital in the Northeast of Brazil. A total of 948 medical records were reviewed. Overall NI incidence rate was 34%. The main neonatal NI was bloodstream infection (68.1%), with clinical sepsis accounting for 47.2%, and pneumonia was the second most common NI (8.6%). Multivariate analysis identified seven independent risk factors for NIs: birth weight, exposure to parenteral nutrition, percutaneous catheter, central venous catheter or mechanical ventilation, abruptio placentae and mother's sexually transmitted disease (STD). Neonates from mothers with STD or abruptio placentae, those weighing less than 1,500 g at birth or those who used invasive devices were at increased risk for acquiring NI.
Databáze: Directory of Open Access Journals